It is a physical method used to separate and or to analyze complex mixtures. The components to be separated are distributed between two phases: a stationary phase (generally a resin bed) and a mobile phase which travels through the stationary bed.
A mixture of various components enters a chromatography process, and the different components are through the system at different rates. These differential rates of migration as the mixture moves over adsorptive materials provide separation. The smaller the affinity a molecule has for the stationary phase, the shorter the time spent in a column.
In any chemical or bio-processing industry, the need to separate and purify a product from a complex mixture is a necessary and important step in the production line.
It is popular because of following reasons
- It can separate complex mixtures with great precision.
- Even very similar components, such as proteins that may only vary by a single amino acid, can be separated.
- It can purify basically any soluble or volatile substance if the right adsorbent material, carrier fluid, and operating conditions are employed.
- It can be used to separate delicate products since the conditions under which it is performed are not typically severe.
- Used for Separation of Chiral Compound.
CleaNsep offers Chromatographic systems for batch as well as continuous application (SMB chromatography system). We offer these systems from laboratory scale to commercial range.
